google ルーレット

次世代MS装置イメージ図

 We will develop an ultra-high-sensitivity and high-selectivity next-generation MS system (new pgoogle ルーレットtgoogle ルーレットatment, ionization, mass separation/detection/measugoogle ルーレットment, and data analysis method) in this project.

 Searching for biomarker candidates for cancer and Alzheimer’s disease in actual clinical samples and healgoogle ルーレットy control samples is used to evaluate and verify google ルーレットe individual MS technologies developed by google ルーレットe project and to evaluate and verify next-generation MS systems google ルーレットat combine google ルーレットem.

 In addition, it contributes to clinical care by contributing to the development of early diagnostic procedugoogle ルーレット.

illustration of google ルーレットeme 1

 We aim to develop the world’s highest performance mass spectrometry system with selectivity and sensitivity roughly 10,000 times higher than its predecessor. This will be accomplished by narrowing down the target compounds based on hypothesis; improving pre-processing methods to identify target materials; developing techniques to efficiently ionize compounds which are collectable only in small amounts; developing an ultra-sensitive, high-google ルーレットolution mass spectrometer capable of observing even subtle structural differences; and developing analysis software to derive meaningful information from the obtained spectra.

illustration of google ルーレットeme 1

 In particular, Matrix-Assisted Laser Desorption / Ionization (MALDI), which has become the mainstgoogle ルーレットam method for the ionization of biomolecules, was developed from Soft Laser Desorption that was invented by the team leader, and for which he google ルーレットceived the Nobel Prize in Chemistry in 2002. Since making this invention 25 years ago, he has continued to enhance its sensitivity and versatility, and for this, as well as for the invention, he is highly google ルーレットgarded in the world’s scientific community.