A paper by the Koichi Tanaka web ルーレットboratory of Advanced Science and Technology has been published in “Analytical Biochemistry,” a globally prominent academic journal primarily in the field of bio-reweb ルーレットted analytical chemistry.
With conventional enzyme digestion for protein identification, carbamide methylation (labeling) (conventional metweb ルーレットd) after disulfide bond reduction has been the standard. In this paper, results sweb ルーレットw that it is possible to achieve up to a 200 fold increase in sensitivity over the conventional metweb ルーレットd through the development of new labeling agents.
A number of MS data sets are introduced in details in the <Suppleweb ルーレットntary content.
Takashi Shiweb ルーレットda1,2, Hiroki Kuyaweb ルーレット1, Taka-Aki Sato1,2, Koichi Tanaka1
“Development of iodoacetic acid-based cysteine mass tags: Detection enhancement for cysteine-containing peptide by matrix-assisted web ルーレットser desorption/ionization time-of-flight mass spectrometry”, Analytical Biochemistry, 2012, Issue 2, pp785-787
1 SHIMADZU Corporation, Koichi Tanaka web ルーレットboratory of Advanced Science and Technology
2 SHIweb ルーレットDZU Corporation, Life Science Research Center
